刚下了avastin官网的用药指南:' }& C% ^' p+ v$ h
$ x' {+ U0 G, p Patients should continue treatment until disease progression or unacceptable toxicity.
, D; T4 O. a: g4 R; d9 V1 Metastatic Colorectal Cancer (mCRC) 4 V, Q M* C$ ]% Q D8 D0 c" f; B
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
' W" }2 V# U, o. @) G. [1 t( X% Qintravenous 5-FU-based chemotherapy. - F% x c& V5 } X q% x6 m" H
• Administer 5 mg/kg when used in combination with bolus-IFL. 6 y& r; Z+ [2 r. }
• Administer 10 mg/kg when used in combination with FOLFOX4. 8 I L: Y/ k5 K
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
. q4 K# w2 G9 d+ n2 i3 `; z# Y The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and 0 c/ C5 k- U+ ]4 D. L
paclitaxel. 9 P7 q" r& l9 g8 k0 K) P
3 Metastatic Breast Cancer (MBC)
6 L- e. t+ ~+ }9 a; n) U5 J The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
$ c$ v$ ?. O6 {7 X1 B1 T9 E( a4 Glioblastoma
. ~ ^. X* G" Z4 I The recommended dose is 10 mg/kg every 2 weeks.
$ n: m8 |4 U9 R5 S% N5 N, y( z5 Metastatic Renal Cell Carcinoma (mRCC)* |' ]; t8 w7 k+ X& P
The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
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K: e, s* H# G, Q! L按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。! G' |' _2 M7 M( |
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |