刚下了avastin官网的用药指南:
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Patients should continue treatment until disease progression or unacceptable toxicity. * B/ G% D. A3 e# j/ y8 s6 [
1 Metastatic Colorectal Cancer (mCRC)
b% l8 K$ A; d The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
& U. ^- L3 d2 r' p" vintravenous 5-FU-based chemotherapy.
( a, Y: m, m Q( n• Administer 5 mg/kg when used in combination with bolus-IFL. * C# z$ ?) c s& X% s* U
• Administer 10 mg/kg when used in combination with FOLFOX4. 5 e" R8 y# H% E" V* c* `" e* ? Q% l. Q
2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC) 2 A* j/ ~" |, l% h* E7 P
The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and 2 j7 [8 @- X$ f
paclitaxel.
0 o6 R/ q( e" g) e+ P G' a3 Metastatic Breast Cancer (MBC) / S3 _' I% m3 u6 n0 e
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
& J& I% u7 O# U8 j- I% d4 Glioblastoma
4 N, m4 x$ u4 a& h( i The recommended dose is 10 mg/kg every 2 weeks. / X* E" Z; F% h
5 Metastatic Renal Cell Carcinoma (mRCC)
7 v/ c( D9 S4 b9 Z: D The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
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2 H5 L1 q) F! ~/ L0 M; ]% h按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。0 H$ E. g, v, u
我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |